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Your research in cancer genomics makes a difference.

  • An estimated 5–10% of all cancers are heritable, which means germline (inherited) mutations contributed to the development of the cancer
  • There are over 300 different inherited cancer syndromes
  • Heritable cancer impacts ~300 million people worldwide, with an additional 1.4 million new cases each year

Reference: Ngeow J, Eng C. Precision medicine in heritable cancer: When somatic tumour testing and germline mutations meet. NPJ Genom Med. 2016;1:15006. PMID: 29263804. DOI: 10.1038/ npjgenmed.2015.6.

In recent years, significant technological improvements in sequencing and analysis tools have empowered researchers to get answers faster and more efficiently than ever before.

Targeted next-generation sequencing (NGS) is an accurate, fast, and precise approach suitable for analyzing multifactorial disorders with known or suspected variants such as cancer, diabetes, and hypertension.

Unlike other NGS approaches, our Ion Torrent focused NGS technology enables the speed, scalability, and precision researchers need to spend more time finding answers and less time looking for them.

Our Ion Torrent focused NGS solution for hereditary cancer genomics (CGx) provides:

  • Customization—Easily configure your gene panel with our convenient selection tool. Select from a catalog of optimized wet lab-tested genes known to be relevant in genetic testing for hereditary cancers. Suitable for germline analysis.
  • Compatibility with degraded sample types—our panels work well with saliva and buccal swabs
  • Low cost per sample—order in smaller pack sizes to help reduce upfront cost and risk from changing project requirements
  • A fast, automated workflow—go from sample to data in as little as 24 hours, with just 45 minutes of hands-on time**
Figure 1. Automated and rapid targeted sequencing workflow using Ion Chef and Ion GeneStudio S5 systems. A manual library and template prep workflow using the Ion OneTouch 2 System is also available. Ion AmpliSeq panels are compatible with all Ion Torrent NGS systems.
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