LC-MS Instruments - Liquid Chromatography Mass Spectrometry

Revolutionary LC-MS systems designed with innovation in mind

Profile, screen, identify, and quantify a wide variety of molecules with confidence using our LC-MS instruments. Whether you are characterizing compounds, identifying contaminants, or quantifying analytes, Thermo Fisher Scientific cutting-edge LC-MS systems offer high sensitivity, resolution, and throughput to meet your evolving scientific needs. Benefit from advanced performance and versatility for your applications in any LC-MS lab. Our instruments are designed to support your laboratory's requirements, ensuring precise and reliable results. Explore the power of our LC-MS instruments and elevate your research with Thermo Fisher LC-MS systems.

Orbitrap Astral MS

Realize a universe of possibilities with faster throughput, deeper coverage, higher sensitivity, and accurate and precise quantitation across applications.

Orbitrap Tribrid MS

For large and small molecule analysis, precisely measure low-abundance peptides in complex matrices and characterize structural isomers and native protein complexes structures.

Orbitrap Excedion Pro MS

Unlock the potential of your analytical workflows. Enhance your research and achieve groundbreaking discoveries with sensitivity and dynamic range.

Stellar MS

Robust quantitation with the specificity of rapid full scan MSn acquisition creates unrivaled improvements in laboratory productivity.

TSQ Plus Triple Quadrupole MS

Address your challenges in routine, targeted quantitation for all molecule types. Achieve excellent sensitivity requirements, robustness, reliability, and speed.

LC-MS Systems Accessories

Specialized ion sources, alternative dissociation techniques, probes that optimize MS workflows and performance to help you obtain the most sensitive data possible.

Built-for-purpose mass detector

Applications

Elevate your research, whether you are deciphering biology’s complexities, bringing biotherapeutics to market, developing crucial pharmaceuticals, or answering real-world health, environmental, or food & beverage safety questions. With LC-MS, which combines the separation power of liquid chromatography with the mass accuracy of a mass spectrometer, you can help accelerate insights to improve human health, protect our environment, and ensure food and water safety.

Proteomics

Discover the biology of cells, tissues, and organisms through the power of proteomics.

Metabolomics & Lipidomics

Decipher small molecules to get broader and deeper insights into metabolite & lipid biology.

Structural Biology

Explore solutions for the determination of structure and function of macromolecules.

BioPharma & Pharma

Accelerate outcomes and experience a smooth transition through your drug discovery and development process.

Translational research

Achieve earlier and more accurate disease detection with transformative biomarker discovery and verification proteomics solutions.

Clinical Research

Develop reproducible, sensitive analytical methods for clinical translational research and sports anti-doping.

Environmental

Discover powerful tools for detection and quantification of per- and polyfluoroalkyl substances (PFAS) compounds in water and soil.

Food & Beverage

Stay on top of pesticide residue analysis, whether your lab is built for research or commercial testing.

Forensic Toxicology

Screen and confirm known compounds, identify unknowns and advance forensic research.

Educational and financial resources

Application insight

See how mass spectrometry solutions can enable your LC-MS laboratory to solve application challenges.

Mass spectrometry affordability programs

Refurbished, trade-in, financing & leasing MS programs to advance your research even with budget challenges.

Advance your grants

Your work, our partnership. Together we can answer the call for scientific 
grants and funding.

Greener by Design

Improve sustainability with dry pumps to reduce noise, heat production, and lower maintenance.

For Research Use Only. Not for use in diagnostic procedures.