Learning Center

Expand your knowledge of HLA antibodies and molecular typing.

Learn the latest HLA technical and clinical advancements in transplant diagnostics. We have hands-on workshops geared to beginner and advanced HLA technicians who want to learn how to troubleshoot and analyze data results. We also host webinars or symposia at global transplant societies, including ASHI, EFI, and BSHI where you can interact with industry leaders to discuss the latest techniques and procedures.


Use the filters below to browse available events & on-demand resources.

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Clinical Applications for MMDx®: Gene Expression Profiling in Transplant Biopsies
Recorded: AUG 29, 2021
Molecular assessment was applied to diagnose allograft dysfunction and to determine if rejection was due to ABMR, TCMR, or a combination of both.
Intensity of de novo DSA detected by Immucor Lifecodes assay and C3d fixing antibodies are not predictive of subclinical ABMR after kidney transplantation
Published: AUG 3, 2021
Bertrand et al. demonstrate that there are significant differences between HLA antibody test vendors in the ability to detect dnDSA in cases of biopsy-proven sABMR.
Are Dilutions the Solution? Identifying the True Extent of Patient Sensitization
Recorded: JUL 21, 2021
In this presentation, Drs. Mark Stegall and Anat Tambur discuss how serial dilutions of the LABScreen™ Single Antigen assay aid in the assessment of alloantibody levels.
Advanced Virtual Workshop Series
Recorded: MAY 26, 2021
Learn how to process samples using LABType, LABScreen, AllType, and LinkSeq products as well as how to create customize analysis reports using HLA Fusion, TypeStream, and SureTyper software.
Research suggests HLA & HNA may play a critical role in COVID-19 Susceptibility, Immune Protection and Success of Novel Treatments during a Global Pandemic Crisis
Published: JUN 10, 2021
We have the requisite HLA and HNA antibody screening products to protect patients from an adverse transfusion-related lung injury during upcoming convalescent plasma therapy trials.
The Quest for Better Kidney Care in Multicultural Communities
Recorded: MAY 18, 2021
Carolyn of Kidneys Quest Foundation discusses the challenges of dialysis patient care in diverse and underserved communities.
A 2020 Banff Antibody Mediated Injury Working Group examination of international practices for diagnosing antibody mediated rejection in kidney transplantation
Published: APR 16, 2021
Biopsy data is accompanied by DSA data in +/- 30% of cases, suggesting urgent action to improve the accessibility of DSA information is needed.
Incidence and impact of allele-specific anti-HLA antibodies and high-resolution HLA genotyping on assessing immunologic compatibility
Published: APR 11, 2021
Allele specific anti-HLA reactivity was shown to occur in around 15% of patients awaiting transplantation.
Analysis of RNA Transcripts by the Molecular Microscope® Diagnostic System (MMDx®) Can Direct Management after Indication Kidney Transplant Biopsy
Published: MAR 16, 2021
These two cases describe how MMDx was used to aid the management of two patients with Banff diagnoses of “borderline” and “Banff 1a TCMR.”
Discrepancy analysis comparing molecular and histology diagnoses in kidney transplant biopsies
Published: MAR 16, 2021
This study demonstrates the reproducibility of MMDx and the lack of significant disagreement between MMDx sign outs.
Innovations in Rejection Surveillance after Heart Transplantation
Recorded: MAR 7, 2021
For post-transplant management in heart patients, the endomyocardial biopsy is considered the gold standard to detect acute rejection.
Gene Expression Profiling for the Identification and Classification of Antibody-Mediated Heart Rejection
Published: MAR 2, 2021
The study describes the molecular landscape of antibody mediated rejection.
COVID Plus: A New Diagnostic Tool to Protect Transplant Patients in the Fight Against COVID-19
Published: MAR 2, 2021
Identifying multiple distinct antibodies to COVID-19 will be vitally important as some have demonstrated neutralizing capabilities
Immune Response to COVID-19 and Vaccination in Transplant Patients
Recorded: MAR 19, 2021
The COVID-19 pandemic has impacted the transplant community disproportionately and remains an important topic in the field of histocompatibility and immunology.
Basic Immunology and the HLA Complex
Recorded: FEB 19, 2021
In the context of transplant medicine, this program will review immunology basics and the structure and function of the HLA complex for both Class I and Class II. 
Revisiting the changes in the Banff Classification for antibody‐mediated rejection after kidney transplantation
Published: FEB 17, 2021
In the search for potential treatments and personalized prognostication, a clear definition of antibody mediated rejection (ABMR) is an indispensable prerequisite.
Estimating Alloantibody Levels in Highly-Sensitized Renal Allograft Candidates
Published: FEB 3, 2021
This study used serial dilution analysis to determine the point at which cPRA could be reduced below 98%, a value previously shown to significantly increase probability of transplant.
Amplifying the Patient Voice: Key Priorities and Opportunities for Improved Transplant and Living Donor Advocacy and Outcomes During COVID-19 and Beyond
Published: JAN 27, 2021
When defining patient advocacy and engagement for modern transplant and living donation care, particularly in light of the COVID-19 pandemic, the authors describe the patient experience when ...
Development and Validation of a Multiplex, Bead-Based Assay to Detect Antibodies Directed Against SARS-CoV-2 Proteins
Published: JAN 14, 2021
A new diagnostic tool to determine SARS-CoV-2 antibody status in transplant patients
EMEA Virtual Workshop
Recorded: DEC 11, 2020
Learn key software functionality for HLA Fusion™ 4.4 and TypeStream™ Visual 2.0.1. Includes challenging LABScreen™, AllType™, and LABType™ case studies, and overview of HLA MatchMaker.
Changing the Conversation on Chronic Illness & Disability
Recorded: DEC 10, 2020
Our W-ERG LA Chapter organized this webinar to discuss the common challenges, biases, and misconceptions that those with a chronic illness or disability often face.
Vein to Vein: RBC Alloimmunization, Genotyping & Inventory Management
Recorded: NOV 17, 2020
Hear from industry leaders as they discuss transfusion medicine, challenges of finding donors, managing blood bank inventory, as well as the benefits of preventing alloimmunization.
Import A LABScreen Session In HLA Fusion™ Software
Recorded: NOV 11, 2020
Follow the step-by-step process in order to import your LABScreen raw data into the HLA Fusion software.
Discovering novel injury features in kidney transplant biopsies associated with TCMR and donor aging
Published: OCT 26, 2020
We previously characterized the molecular changes in acute kidney injury (AKI) and chronic kidney disease (CKD) in kidney transplant biopsies, but parenchymal changes selective for specific types ...
The Power of Digital Storytelling to Educate, Empower, and Engage Patients and Prospective Living Donors
Recorded: OCT 18, 2020
Dr. Amy Waterman with UCLA and the Terasaki Institute for Biomedical Innovation shares how the true stories of transplant donors, recipients, and candidates have the power to save and change lives.
Introduction to the Molecular Microscope Diagnostic System (MMDx)
Recorded: OCT 18, 2020
What is MMDx and how does it work? Dr. Christopher Lawrence gives a brief overview of the biopsy service.
Increasing Access to Transplantation for the Highly Sensitized Patient: Combining the Latest Innovations in HLA Typing, Antibody Detection and Data Analysis.
Recorded: OCT 18, 2020
We explore how the evolution of more efficient NGS workflows and advanced Single Antigen assays with extended allele coverage can improve analysis with Epitope Matching and Virtual Crossmatching.
APAC Virtual Workshop
Recorded: SEP 24, 2020
This session features an overview of SureTyper, TypeStream Visual, HLA Fusion, HLA MatchMaker, and a discussion on the role of HLA Antibodies in transplantation by Dr. Cathi Murphey-Half.
Upload Reference Files in TypeStream™ Visual 2.0
Recorded: SEP 23, 2020
This is a simple tutorial on where to locate and how to download files for TSV analysis.
Update Reference Files in HLA Fusion™ Software
Recorded: SEP 21, 2020
Follow the step-by-step process to ensure you have the most up-to-date reference files to accomplish your analysis within the software.
Specimen Collection Procedure for the Molecular Microscope Diagnostics System (MMDx)
Recorded: SEP 1, 2020
Thinking of ordering an MMDx specimen collection kit? See what's in the kit and how to collect the specimen and ship it to the lab for assessment.
The Role of Race in Transplant and Transfusion: a Roundtable Discussion
Recorded: AUG 31, 2020
HLA experts discuss the need for a more diverse donor pool and the impact that the COVID-19 pandemic is having on minority donor recruitment in transplant and transfusion.
Multiplexed SARS CoV2 Platforms: Future Interactions
Recorded: AUG 25, 2020
Dr. Woodle reviews the body of evidence that suggests SARS-CoV-2 may circumvent many of the typical rules of immune response and discusses the research applications for a multiplex assay as a tool.
What is the LABScreen™ COVID Plus Assay?
Recorded: AUG 25, 2020
Dr. Bray explains how the assay will allow labs to examine the heterogeneity of humoral responses between patients as well as the development of the humoral response in a single patient over time.
Cinical Utility of SARS-CoV-2 Antibody Testing
Recorded: AUG 25, 2020
Dr. Deepali Kumar examines how a multi-antigen assay can help characterize vaccine response and clarify how antibodies present in asymptomatic versus symptomatic patients.
Testing for SARS-CoV-2 Antibodies: How it began
Recorded: AUG 25, 2020
Dr. Howard Gebel shares the need for an assay that is comprehensive, specific, and sensitive enough to build a complete antibody profile for patients exposed to the COVID-19 virus.
Assessment of the Humoral Response to SARS-CoV-2 Infection Via Novel Multiplexed Assays
Recorded: OCT 18, 2020
Discussion on what we currently know about the humoral response to the SARS-CoV-2 virus and explore the clinical and research applications of using a multiplexed assay to test for COVID-19 antibodies.
LATAM Virtual Workshop
Recorded: JUL 20, 2020
This session includes an introduction to the HLA Fusion 4.4 functionality, a review of challenging LABType and LABScreen case studies, and a discussion on the role of HLA Antibodies in transplantation
Virtual crossmatch strategy to facilitate kidney transplantation for highly sensitized candidates
Recorded: JUN 30, 2020
In this talk, Dr. Raja delves into key considerations for highly sensitized candidates.
Recovering from the COVID-19 Crisis in Transplantation – A Roundtable Discussion
Recorded: MAY 28, 2020
Doctors Robert Liwski and Bob Bray lead a discussion on how centers are managing operations and patient care during the ongoing pandemic.
The Quest to Decipher HLA Immunogenicity: Telling Friend from Foe
Recorded: MAY 26, 2020
Dr. Tambur explores a new way to interrogate molecular mismatch load and discusses important concepts in immunogenicity.
Introduction to the AllType™ FASTplex™ Protocol
Recorded: MAY 18, 2020
Learn about the streamlined Illumina workflow and kit configuration of the newest AllType FASTplex NGS protocol, and discover how your run step will be simplified with our new Calculator Tool.
The Kinetics of Anti-HLA Antibody in Simultaneous Liver-Kidney Transplantation
Recorded: APR 28, 2020
Dr. Matthew Cusick will provide an assessment of the impact that DSAs may have on simultaneous liver-kidney transplants and discuss how the liver may play a key role in antibody clearance.
Analyze LinkSēq™ HLA Typing Kits using SureTyper™ Software v6.0
Recorded: MAR 2, 2021
Learn how to analyze LinkSēq HLA Typing Kits using the SureTyper Software version 6.0.
Allele-specific DSA: Lessons from SAB and NGS
Recorded: FEB 27, 2020
Dr. Morris explores the limitations of solid-organ HLA genotyping methods that may preclude DSA identification and discussed various approaches for monitoring allele-specific anti-HLA antibodies. 
AllType™ Next Generation Sequencing – Easy Integration and Future Innovation
Recorded: JUL 22, 2019
Elizabeth Wroe showcased the NHSBT’s rigorous selection criteria and provided an in-depth look of the lab’s integration of the AllType NGS assay into routine laboratory practice.
New Frontiers in Expanded Single Antigen Testing
Recorded: JUN 26, 2019
Dr. Jakob Nilsson gives a preliminary summary of his experience using LABScreen Single Antigen ExPlex, and assesses the test’s ability to predict possible binding epitopes through HLAMatchmaker.
The Evolution of Risk Assessment in Solid Organ Transplantation
Recorded: MAY 29, 2019
Dr. Kelley Hitchman gives an overview of advancements in crossmatch testing, examines the practicality and advantages of virtual crossmatching, and reviews requirements that impact labs.
The Molecular Microscope Diagnostic System: Precision and Accuracy in Transplant Diagnostics
Recorded: APR 29, 2020
Dr. Phil Halloran discusses the unmet need for precision and accuracy in pathological biopsy assessment and reviews the applications of the actionable data generated in MMDx reports.
The Usefulness of Epitope Analysis When Interpreting HLA Antibody Test Results
Recorded: MAR 22, 2019
Dr. Robert Liwski provides an overview of the HLAMatchmaker approach and explores the key role of epitope analysis in HLA antibody testing through literature review and case studies.
Assessing HLA Antibodies: Can we understand the strength?
Recorded: JUN 28, 2018
Learn about HLA antibody testing, interpretation of HLA antibody profiles, and the utility of serum dilution and C1qScreen in this discussion led by Dr. Nicole Valenzuela.
Analyzing the AllType™ NGS Assay using TypeStream™ Visual Software - Version 1.2
Recorded: JUN 11, 2018
The course introduces the TypeStream Visual Software and guides you through the analysis of various samples including one "Typical Case" and several "Special Cases".
ABO Blood Subgrouping and Implications in Transplantation
Recorded: MAY 31, 2018
Understand ABO genotyping, how it enables ABO minor incompatible (ABOi) transplants and the technologies and resources that are available to help labs perform ABOi transplants.
Validation of HLA Typing by NGS
Recorded: MAY 23, 2018
Includes a summary of NGS validation procedures, in-depth analysis of quality control measures, as well as pre-implementation cost analysis and preparation of the ASHI submission packet.
Non-HLA Antibodies: A New Perspective on Allograft Injury & Rejection
Recorded: FEB 14, 2018
Dr. Jackson, provides a detailed introduction to non-HLA antibodies, discusses their potential impact to transplantation, and reviews new developments in their characterization.