One Lambda Devyser Chimerism for NGS

Detect micro-chimerism earlier and monitor against graft rejection

Advanced Chimerism Testing for Post Hematopoietic Stem Cell (HSCT) Transplant Monitoring

When it comes to monitoring bone marrow transplants, chimerism analysis is an integral part of molecular transplant monitoring and serves as a crucial tool for healthcare professionals. It helps them assess the success of the procedure, detect any potential issues, and make informed decisions. Detect graft rejection and disease relapse at an early stage with the One Lambda™ Devyser™ Chimerism advanced testing solution. With our highly sensitive test, you can quickly identify the recipient microchimerism that may be a sign for graft rejection and disease relapse at a very early stage. Maximize the test outcomes and ensure the success of your transplant programs with our cutting-edge chimerism testing solution.

Want to start tracking chimerism in HSCT for enhanced care?

Ask us about the One Lambda Devyser Chimerism NGS assay.

What is the One Lambda Devyser Chimerism Assay?

The Next Generation of Chimerism Testing

Designed to provide accurate and sensitive detection of microchimerism levels in stem cell transplant samples, the One Lambda Devyser Chimerism NGS assay is a post-transplant monitoring solution that is perfect for HLA and molecular core labs associated with HSCT Programs. It offers a fast and repeatable workflow from patient sample to report and a unified workflow for screening and monitoring. One tube per sample avoids any need for sample splitting, and the single measurement method is independent of mixed chimerism levels. Leveraging next-generation sequencing (NGS) technology, our assay offers an unparalleled limit of detection of 0.05%, enabling the identification of even the smallest changes in chimerism status.

Assay Key Features & Benefits

  • Comprehensive Coverage: Utilizes 24 indel markers to detect microchimerism in post-HSCT samples.
  • Confidence in Results: Achieves accurate results with sensitivity to >0.05%
  • Efficient Workflow: Utilize a single universal mix and one workflow for both screening and monitoring, reduces hands-on time to 45 minutes, and delivers next-day sequencing results.
  • Simplified Analysis: User-friendly Software simplifies chimerism assessment, enables flexible data presentation, and provides longitudinal tracking, all within one dedicated software

How Does the One Lambda Devyser Chimerism Assay Work?

Seamless Workflow for Maximum Efficiency

Our One Lambda Devyser Chimerism NGS assay offers a seamless workflow that requires up to 45 minutes of hands-on time, delivers results the next day, and ensures maximum efficiency in your laboratory. By utilizing a single protocol, you can easily perform both screening and monitoring together and eliminate the need for sample-specific primers and patient-specific marker tracking. The universal reagent mix allows for cost-effective testing, reducing reagent wastage and the need to keep multiple reagents in stock.

Highly Accurate Results with Unmatched Sensitivity

The One Lambda Devyser Chimerism NGS assay combines the sensitivity of real-time PCR analysis and the precision of STR-based analysis. The unique 24-indel panel allows for accurate detection and monitoring of microchimerism, irrespective of mixed chimerism levels. With one tube per sample, there's no need for sample splitting, ensuring optimal sample integrity and reliable results.

Dedicated Software for Fast and Accurate Result Analysis

You can easily assess chimerism, sample type, and longitudinal tracking with the One Lambda Devyser Chimerism NGS assay and its dedicated software. The dedicated data analysis software delivers precise and speedy chimerism status information. The user-friendly interface and flexible data display simplify data interpretation. With this comprehensive sample-to-result solution, you can optimize your lab resources while providing top-quality results.

Unlock the Full Potential of Chimerism Testing

Increase your post-transplant monitoring capabilities and join the next generation of chimerism testing with the One Lambda Devyser Chimerism NGS assay. Detect microchimerism and monitor graft rejection and disease relapse in stem cell transplant at an early stage, enabling timely interventions and improved transplant outcomes.

Take control of graft rejection and disease relapse detection with One Lambda Devyser Chimerism for NGS.
Ask about our advanced chimerism testing solution today.

Advanced Molecular Transplant Monitoring Solutions with The Devyser and Thermo Fisher Scientific Partnership

The partnership between Devyser and Thermo Fisher Scientific combines expertise and resources to offer enhanced and cutting-edge molecular transplant monitoring capabilities to transplant programs, HLA labs, and transplant clinicians. Backed by Thermo Fisher Scientific's robust commercial infrastructure, our collaboration ensures reliable, accurate, and high-quality testing solutions for healthcare providers worldwide.

Explore Product Details

One Lambda Devyser Chimerism Assays
Targeted NGS assays that utilize Indel markers to measure the Chimerism in a patient sample. For Use on Illumina MiSeq, MiniSeq, and iSeq Systems.
Advyser Chimerism Software
The software analyzes NGS data generated with an Illumina sequencer: Screening of informative markers and monitoring of chimerism status in tested samples

Product is CE marked but not 510(k)-cleared and not available for sale in the U.S. Availability of product in each country depends on local regulatory marketing authorization status.