GeneBLAzer™ CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells contain the human Calcitonin Gene Related Peptide Receptor (CALCRL:RAMP1), (Accession # NM_005795.3 NM_005855.2) stably integrated into the CellSensor™ CRE-bla Freestyle™ 293F cell line. CellSensor™ CRE-bla Freestyle™ 293F cells (Cat # K1130) contain a beta-lactamase (bla) reporter gene under control of the cAMP response element (CRE).
CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells are functionally validated for Z'-factor and EC50 concentrations of Alpha-CGRP. In addition, CALCRL:RAMP1-CRE-bla FreeStyle™ 293F cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_005855.2
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
Gene Symbol
CALCRL:RAMP1
Population Status
Single Cell Clone Origin
Product Line
Freestyle™, GeneBLAzer™
Reporter Gene
BLA (Beta-Lactamase)
Target Entry
CALCRL:RAMP1
Cell Line
FreeStyle 293-F Cells
System Type
GeneBLAzer™
Druggable Target
GPCR
Contents & Storage
(LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol).