GeneBLAzer® TACR2-NFAT-bla CHO-K1 cells contain the human Tachykinin receptor 2 (TACR2), (Accession # NM_001057) stably integrated into the CellSensor® NFAT-bla CHO-K1 cell line. CellSensor® NFAT-bla CHO-K1 cells (Cat. no.K1078) contain a beta-lactamase reporter gene under control of the NFAT Response Element. TACR2-NFAT-bla CHO-K1 cells are functionally validated for Z’-factor and EC50 concentrations of (Nle10)-Neurokinin A (4-10) (Figure 1). In addition, TACR2-NFAT-bla CHO-K1 cells have been tested for assay performance under variable conditions.
For Research Use Only. Not for use in diagnostic procedures.
Specifications
Accession Number
NM_001057
Assay Entry
Cell-based beta lactamase reporter gene
Cell State
Dividing Cells
Detection Method
Fluorescent
For Use With (Application)
FRET
Gene Symbol
TACR2
Human Protein Class
G-Protein Coupled Receptor (GPCR)
Population Status
Pool of Stable Cells
Product Line
GeneBLAzer™
Readout
End Point
Target Entry
TACR2
Cell Line
CHO-K1
System Type
GeneBLAzer™
Druggable Target
GPCR
Contents & Storage
K1844 GeneBLAzer™ TACR2-NFAT-bla CHO-K1 cells (LiveBLAzer™-FRET B⁄G Loading Kit, Solution D and other materials are required separately; please refer to the protocol). Includes: • GeneBLAzer™ TACR2-NFAT-bla CHO-K1 cells • GeneBLAzer™ TACR2-NFAT-bla CHO-K1 Assay Protocol • Certificate of Analysis The GeneBLAzer™ TACR2-NFAT-bla CHO-K1 cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.