Microspheres (also called latex beads or latex particles) are spherical particles in the colloidal size range that are formed from an amorphous polymer such as polystyrene. Because of the way that the polystyrene chains arrange themselves in the bead, the surface is very hydrophobic in character, making these ideal materials for the adsorption of materials such as proteins.

This positively-charged hydrophobic amidine latex is particularly suited for the preparation of latex intermediates. The only surface functional group present on the particle is amidine, which is not sensitive to the aggregating effects of polyvalent cations. These particles are sensitive to negatively charged contaminants or multivalent anions. The amidine latexes should be used in low to neutral pH environments. The amidine group is a base and with a pK ∼10-11.

Microspheres Are Available in Many Sizes and Surface Functionalities
• 25 sizes to choose from—0.02 microns to 16 microns
• 20 different surface—for ready conjugation to virtually any material
• Surfactant free—ultraclean
• Various quantities—from milliliter to 500-liter amounts

Key Applications of Microspheres
• Instrument calibration (flow cytometry, microscopy, HTS, HCS)
• Flow testing (microfluidics, blood flow, water flow, and air flow)
• Cell biology tracers (cell differentiation and cell tracing)
• Immunoassays (agglutination tests, ELISA, particle capture, and contrast reagents)

Get More Information
Read a technical overview of microspheres and find out about high activity beads, super active beads, specialty beads, and review bead-coupling protocols on the IDC Surfactant-free Latex Beads application page.

We’ll Make a Custom Microsphere Product for You
If you don’t see the microsphere you’re looking for in our stocked list, we’ll make a custom microsphere for you. Our custom conjugation service is efficient and confidential, and we guarantee the quality of our work. We are ISO 13485:2000 certified.

For Research Use Only. Not intended for animal or human therapeutic or diagnostic use.