SYBR Safe™ DNA gel stain was developed specifically for reduced mutagenicity—to be safer than ethidium bromide for staining DNA in agarose or acrylamide gels. SYBR Safe™stain is not only less mutagenic than ethidium bromide, but SYBR Safe™ stain's detection sensitivity is better than that of ethidium bromide. SYBR Safe™ stain comes as a premixed solution that can be used just like an ethidium bromide solution, either in the gel during the electrophoresis run or as a post-run stain. Bound to nucleic acids, the green-fluorescent SYBR Safe™ stain has fluorescence excitation maxima at ∼280 and ∼502 nm, and an emission maximum at ∼530 nm.