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Integrate capillary electrophoresis (CE) and electrospray ionization (ESI) into a single microfluidic device to rapidly prepare, separate, and electrospray biological samples directly into a mass spectrometer (MS). The portable size ZipChip Interface directly mounts onto select models of Thermo Scientific™ mass spectrometers, and creates a seamless CE/ESI-MS workflow that offers fast CE separation, nano-spray level sensitivity, and HRAM spectrometry for the characterization of intact proteins, antibody drug conjugates, antibody subunits, peptides, and metabolites.
Catalog Number
00950-01-00493
Unit Size
Each
Description
ZipChip Interface (Manual version)
Price (USD)
| Type | CE/ESI Interface |
| Software | ZipChip Software |
| Description | ZipChip Interface (Manual version) |
| For Use With (Equipment) | Mass Spectrometers with CE/ESI |
| Unit Size | Each |
Catalog Number
Unit Size
Each
Description
ZipChip Interface (Autosampler version)
Price (USD)
| Type | CE/ESI Interface |
| Software | ZipChip Software |
| Description | ZipChip Interface (Autosampler version) |
| For Use With (Equipment) | Mass Spectrometers with CE/ESI |
| Unit Size | Each |
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| Catalog Number | Specifications | Unit Size | Description | Price (USD) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 00950-01-00493 | Each | ZipChip Interface (Manual version) | Request A Quote | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 00950-01-00492 | Each | ZipChip Interface (Autosampler version) | Request A Quote | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Fast, sensitive, minimal sample preparation and consumption
- Fast run times; most analyses can be done within 2-3 minutes
- High sensitivity; stable nano-spray and nano-spray level sensitivity
- Low (picogram to nanogram) sample consumption
- Minimal sample preparation with online desalting
Compatible sample matrices include but not limited to:
- Cell culture media
- Cell lysates
- Blood
- Plasma
- Urine
Use the ZipChip Interface with Thermo Scientific™ Q Exactive™, Exactive™, Orbitrap Elite™, and LTQ Orbitrap XL™ mass spectrometers.
ZipChip autosampler*Inject samples from vials or 96 well plates and achieve unattended 3-minute sample runs using the ZipChip Autosampler with the ZipChip Interface.
Choice of chips*- ZipChip HS has a shorter separation channel with the shortest run times, and can be used for small molecule, peptides, metabolites, and simple samples.
- ZipChip HR has a longer separation channel for run times that are a little longer. The HR chip can be used for analysis of intact proteins, ADCs, antibody sub-units, complex samples, and when better resolution is required.
Assay kits contain background electrolyte and sample diluent. They are convenient and reduce risk of error. Three assay kits are available:
- Intact Protein Assay Kit
- Peptide Mapping Assay Kit
- Metabolite Assay Kit
*sold separately
The ZipChip Interface is a Class 1 laser product in compliance with 21 CFR 1040.10 and 1040.11 except for deviations pursuant to laser notice No. 50.
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