Thermo Scientific™

ZipChip™ Interface HR and HS Chips

Related applications:

Industrial Mass Spectrometry

Choose between two chips for use on your ZipChip™ Interface. The ZipChip Interface desalts, performs capillary electrophoresis (CE) separation, and nano-electrosprays a wide range of biological samples directly into Thermo Scientific™ mass spectrometer (MS) systems within a few minutes. A built-in chip recognition system allows ZipChip software to recognize the type of the chip, automatically set appropriate operational parameters and track chip usage.

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Two types of chips suit for different analysis:
  • ZipChip™ HS has a shorter separation channel, and suits for small molecules, metabolites, or simple sample mixture
  • ZipChip™ HR has a longer separation channel, and suits for intact proteins, antibody drug conjugates (ADCs), antibody sub-units, or complex sample mixture
Compatible sample matrices include but not limited to:
  • Cell culture media
  • Cell lysates
  • Blood
  • Plasma
  • Urine
Fast, sensitive, convenient
  • Fast run times; most analyses can be done within 2-3 minutes
  • High sensitivity; stable nano-spray and nano-spray level sensitivity
  • Low (picogram to nanogram) sample consumption
  • Minimal to no sample preparation with online desalting