1-Chlorobutane is used as intermediates and solvents. It is used for HPLC, spectrophotometry and environmental testing. It is used as alkylating reagent in organic and organometallic compound synthesis. It is also employed as an antihelmintic in veterinary medicine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.