For high-resolution, high efficiency analysis of monoclonal antibodies (mAbs) and associated variants, use Thermo Scientific™ MAbPac™ SCX-10 RS Monoclonal Antibody Analysis Columns, 5μm. The unique nonporous pellicular resin provides the resolving power to separate mAb variants that differ by as little as one charged residue. A hydrophilic layer surrounds the polymeric beads and eliminates hydrophobic interactions with the resin, resulting in very efficient peaks. A proprietary grafted cation-exchange surface provides pH selectivity control for high-resolution separations.

• Exceptionally high resolution for mAb variants
• Ideal for characterization and quality control assessment of mAbs
• Well-suited for stability studies, mAb therapeutic method development, and high-throughput screening
• Unmatched column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing
• Meets the regulatory requirements for biopharmaceutical characterization
• Available in 3, 5, and 10μm particle sizes in standard and UHPLC formats. The smaller-particle-size columns provide the same resolution as the 10μm columns, but with significantly faster analysis time.