DNAPac™ RP Columns
DNAPac™ RP Columns
Thermo Scientific™

DNAPac™ RP Columns

Get high resolution LC and LC-MS separation of oligonucleotides, including double-stranded (ds) DNA/RNA fragments, using these DNAPac reversed phase columns.

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Catalog NumberLength (Metric)Diameter (Metric)
08892510 mm2.1 mm
088919100 mm3 mm
08892050 mm3 mm
SP6998150 mm10 mm
08892110 mm3 mm
088923100 mm2.1 mm
08892450 mm2.1 mm
303324250 mm2.1 mm
080922-012123210 mm21.2 mm
080922-1521232150 mm21.2 mm
950-0010 mm21.2 mm
11 Options
Catalog number 088925
Price (USD)/ Each
261.26
Add to cart
Length (Metric):
10 mm
Diameter (Metric):
2.1 mm
Price (USD)/ Each
261.26
Add to cart
DNAPac™ RP Columns
Catalog number088925
Price (USD)/ Each
261.26
-
Add to cart

Achieve superior reversed phase oligonucleotide separations using the Thermo Scientific™ DNAPac™ RP HPLC columns. The unique chemistry is designed for analysis of oligonucleotides and double-stranded (ds) DNA/RNA fragments using LC-UV or LC-MS. The column chemistry provides excellent performance under a broad range of pH, temperature, and mobile phase compositions. In addition, the wide pore size of the resin provides excellent separation of large double-stranded nucleic acids up to 10k base pairs.

High Performance Reversed-Phase LC Columns

The DNAPac RP column is based on spherical wide-pore 4μm polymer resin. The phase is highly stable to extremes of pH (0-14), and temperature (5-110°C), and operates with mobile phases compatible with direct mass spectrometry. The column may be operated in both HPLC and UHPLC instruments, producing high resolution at high throughput for oligonucleotides and resolves both small and very large dsDNA segments. DNAPac RP reversed phase (RP) column is specifically designed for separation of oligonucleotides and DNA/RNA fragments. The stationary phase is fully compatible with mass spectrometry friendly organic solvents and ion-pair reagents such as triethylamine (TEA) and hexylamine (HA). The wide pore size of polymer resin enables efficient separation of large nucleic acids with low carry-over.

Columns designed for reversed phase oligonucleotide LC and LC/MS separations
  • Designed for ion-pair reversed-phase (IP-RP) separations of both oligonucleotides and double-stranded nucleic acids
  • High resolution and high throughput
  • Excellent MS compatibility
  • Wide operating pH range (0-14) and high temperature stability (up to 110°C)
Specifications
Column FormatGuard Cartridge
Diameter (Metric)2.1 mm
Length (Metric)10 mm
Max. Pressure4000 psi (275 bar)
Particle Size4 μm
pH0 to 14
Pore SizeProprietary Wide Pore
Quantity2 Pk.
Temperature<110°C
Stationary PhaseDVB (Divinylbenzene) Polymer
Product LineDNAPac
Packing MaterialDVB (Divinylbenzene) Polymer
Column TypeReversed Phase
PhaseReversed Phase
TechniqueBio-LC
Unit SizeEach