Enhance the quality of your mass spectrometry (MS) data by reducing interference from contaminants using the on-line Thermo Scientific™ MSPac™ DS-10 Desalter Cartridge. For use in MS analyses, the desalter minimizes ion suppression and interference caused by salts and contaminents present in biological samples. The MSPac DS-10 Desalter is compatible with salt-based fraction analysis, and has a high loading capacity over a wide pH range for laboratories requiring high sample throughput and increased confidence in their MS analysis.
The high-capacity desalter is based on 5µm porous copolymer beads and is used for the on-line desalting of biological samples for analysis by reversed-phase LC-MS. The high loading capacity of the desalter makes it suitable for use in identification and quantitation in clinical research, biomarker discovery and systems biology applications.
New on-line desalter—built for compatibility with LC-MS analysis
Low peak carryover for sample to sample confidence
High capacity for antibody and protein desalting for identification, biomarker discovery and systems biology. 0.01 to 10µg
High pH stability for superior lifetime with high pH samples
Use with salt-based fractions from ion-exchange (IEX) chromatography, pH-gradient, size-exclusion chromatography (SEC), and more
Improved sensitivity in LC-MS analysis The MSPac DS-10 Desalter Cartridge reduces background contamination and noise seen in LC-MS analysis of samples containing nonvolatile salts. Removing these salts prior to analysis enhances analyte response and improves sensitivity aiding a more reliable identification.