The high-capacity desalter is based on 5µm porous copolymer beads and is used for the on-line desalting of biological samples for analysis by reversed-phase LC-MS. The high loading capacity of the desalter makes it suitable for use in identification and quantitation in clinical research, biomarker discovery and systems biology applications. New on-line desalter—built for compatibility with LC-MS analysis
Improved sensitivity in LC-MS analysis
- Low peak carryover for sample to sample confidence
- High capacity for antibody and protein desalting for identification, biomarker discovery and systems biology. 0.01 to 10µg
- High pH stability for superior lifetime with high pH samples
- Use with salt-based fractions from ion-exchange (IEX) chromatography, pH-gradient, size-exclusion chromatography (SEC), and more
The MSPac DS-10 Desalter Cartridge reduces background contamination and noise seen in LC-MS analysis of samples containing nonvolatile salts. Removing these salts prior to analysis enhances analyte response and improves sensitivity aiding a more reliable identification.