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BMPR1A, Recombinant Human Protein (without catalytic activity domain), hIgG1-Fc.His tag

Catalog number: 10446H03H50

 Related applications: Protein Assays and Analysis

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Bone Morphogenetic Protein Receptor, Type Ia (BMPR1A), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in analysis of protein structure, and performing cell based assays. It can also be used as an immunogen, as a protein standard, or in other research applications.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies.

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Arg 152) of human ALK3 (NP_004320.2) fused to the C-terminal polyhistidine-tagged Fc region of human IgG1 at the C-terminus.

Activity: Measured by its ability to inhibit BMP4 induced activity in MC3T3-E1 Mouse osteoblastic cells. The ED50 for this effect is typically 0.1-0.3 µg/ml in the presence of 50 ng/ml of recombinant human BMP4.

Formulation:140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.

For Research Use Only. Not for use in diagnostic procedures.


Purity: ≥ 85% by SDS-PAGE
Gene ID: 657
Species: Human
Expression: Mammalian
Gene Symbol: BMPR1A
Gene Aliases: ACVRLK3, ALK3, CD292, BMPR1A
Product Size: 50 µg
Protein Form: Truncated, Recombinant
Purification: PAGE
Protein Family: Growth Factors & Receptors
Endotoxin Level: < 1 EU/µg
Molecular Weight: 42 kDa
Research Category: Signal Transduction, Bone Research, Differentiation, Genetic Diseases
Protein Tag or Fusion: hIgG1-Fc His
Validated Application: Assay Standard

Contents & storage

Includes 1 vial of protein in suspension buffer. Store at -5 to -30°C.


Manuals & protocols

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