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FGFR4 Recombinant Human Protein (without Catalytic Activity Domain), hIgG1-Fc Tag

Catalog number: 10538H02H25

 Related applications: Protein Assays and Analysis

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Description

Fibroblast growth factor receptor 4 (FGFR4), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in performing cell based assays. It can also be used as a protein standard, or in other research applications.

Since this product is a truncated protein and does not contain intracellular catalytic activity domain, it is not suitable for use in enzyme activity studies..

This recombinant protein was expressed from a DNA sequence encoding the extracellular domain (Met 1-Asp 369) of human FGFR4 precursor (NP_002002.3) fused to the Fc region of human IgG1 at the C-terminus.

Activity: Measured by its ability to inhibit FGF1-dependent proliferation of BALB/c 3T3 mouse fibroblasts. The ED50 for this effect is typically 2-6 ng/ml.

Formulation: Lyophilized in PBS, pH7.4, 5% Mannitol, 5% Trehalose, and 0.02% Tween-80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by SINO Biological.

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Endotoxin Level: < 1 EU/µg
Expression: Mammalian
Form: Lyophilized
Gene Aliases: FGFR4, CD334, JTK2, MGC20292, TKF
Gene ID: 2264
Gene Symbol: FGFR4
Kinase Family: FGF Receptor Kinase Family
Molecular Weight: 66 kDa
Product Size: 5 x 5 µg
Protein Family: Growth Factors & Receptors
Protein Form: Recombinant, Truncated
Protein Subtype: FGFs (Fibroblast Growth Factors), Receptor Tyrosine Kinases
Protein Tag or Fusion: IgG1 Fc Tag
Purity: ≥ 85% by SDS-PAGE
Research Category: Cardiovascular Research, Immunology, Neurobiology, Oncology, Signal Transduction, Stem Cell Research
Species: Human
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C

Documents

Manuals & protocols

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