Dynabeads™ Human T-Expander CD3/CD28 is intended for separation, activation and expansion of human T cells. Dynabeads™ Human T-Expander CD3/CD28 is the research grade version of Dynabeads™ CD3/CD28 CTS™. Containing the same amount and ratio of antibodies from the same clones as Dynabeads™ CD3/CD28 CTS™, Dynabeads™ Human T-Expander CD3/CD28 are intended for small scale pre-clinical research. Dynabeads™ Human T-Expander CD3/CD28 offers a simple method for activation and expansion of T-cells that does not require antigen presenting cells or antigen. By combining anti-CD3 and anti-CD28 antibodies on Dynabeads™, the beads provide both the primary and co-stimulatory signals that are required for activation and expansion of T cells.

Applications:
Dynabeads™ Human T-Expander CD3/CD28 is the research grade version of Dynabeads™ CD3/CD28 CTS™. The Dynabeads™ CD3/CD28 CTS™ technology has been successfully used in ex vivo separation, activation and expansion of T-cells in a number of studies, including studies on HIV infection and cancer. Other potential applications for this novel technology are treatment of autoimmune and infectious diseases and prevention of complications associated with chemotherapy and allogeneic transplantation.