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Proteintech
ING2 Polyclonal Antibody
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Product Details
11560-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ING2 Fusion Protein Ag2121 (1-280 aa encoded by BC030128)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
11560-1-AP is a rabbit polyclonal antibody raised against full length ING2 of human origin.
Immunogen sequence: MLGQQQQQL YSSAALLTGE RSRLLTCYVQ DYLECVESLP HDMQRNVSVL RELDNKYQET LKEIDDVYEK YKKEDDLNQK KRLQQLLQRA LINSQELGDE KIQIVTQMLE LVENRARQME LHSQCFQDPA ESERASDKAK MDSSQPERSS RRPRRQRTSE SRDLCHMANG IEDCDDQPPK EKKSKSAKKK KRSKAKQERE ASPVEFAIDP NEPTYCLCNQ VSYGEMIGCD NEQCPIEWFH FSCVSLTYKP KGKWYCPKCR GDNEKTMDKS TEKTKKDRRS R (1-280 aa encoded by BC030128)
Target Information
This gene is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ING1Lp; Inhibitor of growth 1-like protein; Inhibitor of growth protein 2; p32; p33ING2; unnamed protein product
Gene Aliases: 2810011M06Rik; ING1L; ING2; Ing2b; P33ING2
UniProt ID: (Human) Q9H160, (Mouse) Q9ESK4
Entrez Gene ID: (Human) 3622, (Mouse) 69260, (Rat) 290744
DNA binding
chromatin binding
protein binding
zinc ion binding
histone deacetylase regulator activity
phosphatidylinositol binding
macromolecular complex binding
metal ion binding
histone H3K4me3 reader activity
histone reader activity
protein complex binding
methylated histone binding
molecular_function
chromatin/chromatin-binding, or -regulatory protein
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
male meiosis I
signal transduction
spermatogenesis
spermatid development
sperm motility
negative regulation of cell migration
positive regulation of transforming growth factor beta receptor signaling pathway
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of gene expression, epigenetic
positive regulation of transcription, DNA-templated
male germ-line stem cell asymmetric division
seminiferous tubule development
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of stem cell population maintenance
positive regulation of stem cell population maintenance
regulation of cellular senescence
negative regulation of apoptotic signaling pathway
transcription, DNA-templated
negative regulation of cell proliferation
chromatin modification
regulation of growth
positive regulation of apoptotic process
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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