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NRG1 Recombinant Human Protein, hIgG1-Fc Tag

Catalog number: 11609H01H5

 Related applications: Protein Assays and Analysis

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Neuregulin 1 (NRG1), recombinant human protein is supplied as a lyophilized powder. It is suitable for use in protein studies such as protein structure analysis and protein-protein interactions. In general, recombinant proteins can also be used as an immunogen, as a protein standard, or in cell biology research applications.

This recombinant protein was expressed from a DNA sequence encoding the EGF-like domain (Thr 176-Lys 246)of human NRG1 (Q02297-6) fused to the Fc region of human IgG1 at the N-terminus.

Activity: Measured by its binding ability in a functional ELISA.

1. Immobilized Rhesus ErbB3 at 2 µg/ml (100 µl/well) can bind human NRG1 (isoform Beta1). The EC50 of human NRG1 (isoform Beta1) is typically 0.58 µg/ml.

2. Immobilized human ErbB3 at 2 µg/ml (100 µl/well) can bind human NRG1 (isoform Beta1). The EC50 of human NRG1 (isoform Beta1) is typically 0.43 µg/ml.

Formulation: Lyophilized in 140 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, pH 7.4, 5% Mannitol, 5% Trehalose, 0.02% Tween 80.

Reconstitution: Dissolve the protein in sterile double distilled water to a concentration of 0.2 mg/ml or lower. It is recommended that the protein be aliquoted and be used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: Expires one year from date of receipt when stored as instructed.

This protein is manufactured by Sino Biological Inc.
For Research Use Only. Not for use in diagnostic procedures.


Form: Lyophilized
Purity: ≥ 85% by SDS-PAGE
Species: Human
Expression: Mammalian
Gene Symbol: NRG1
Gene Aliases: ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, NDF, SMDF
Product Size: 5 µg
Protein Family: Growth Factors & Receptors
Endotoxin Level: < 1 EU/µg
Protein Subtype: Other Growth Factors
Molecular Weight: 36.7 kDa
Research Category: Signal Transduction, Oncology, Development, Biomarker-Related Pathway(s)
Protein Tag or Fusion: IgG1 Fc Tag
Validated Application: Assay Standard

Contents & storage

Includes 1 vial of lyophilized protein. Store at -20 °C.


Manuals & protocols

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