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CD19 Recombinant Human Protein, His tag

Catalog number: 11880H08H25

 Related applications: Protein Assays and Analysis

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Manufactured by Sino Biological (China); Distributed by Life Technologies.

Cluster of Differentiation 19 (CD19) recombinant human protein is supplied as a lyophilized powder. This protein is suitable for use in analysis of protein structure the study of protein-protein interactions, and cell biology research applications. It can also be used as an immunogen, or as a protein standard.

This recombinant protein is expressed from a DNA sequence encoding the extracellular domain (Met 1-Lys 291) of human CD19 (AAB60697) fused to a polyhistidine tag at the C-terminus.

N-terminal Sequence Analysis: Pro 20.

Activity: measured by its binding ability in a functional ELISA . Immobilized human CD19 at 2 µg/mL(100 µL/well) has been shown to bind biotinylated human CD9 with a linear range of 0.032-0.8 µg/mL.

Formulation: lyophilized in PBS, pH 7.4, 5% mannitol, 5% trehalose, and 0.02% Tween®-80.

Reconstitution: Dissolve the protein in sterile double-distilled water to a concentration of 0.2 mg/mL or lower. It is recommended that the protein be aliquoted and used as soon as possible. Store aliquots under sterile conditions at -20°C. Avoid repeated freeze-thaw cycles.

Expiration Date: expires one year from date of receipt when stored as instructed.

Cluster of Differentiation 19 (CD19), is a single-pass type I membrane protein which contains two Ig-like C2-type (immunoglobulinlike) domains. CD19 forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. It interacts with VAV. It interacts with GRB2 and SOS when phosphorylated on Tyr-348 and/or Tyr-378. CD19 also interacts with PLCG2 when phosphorylated on Tyr-409. CD19 is an important pan B cell marker and co-stimulatory protein in humans and mice. CD19 is a hallmark differentiation antigen of the B cell lineage and positively regulates antigen receptor signal transduction in mature B cells. CD19 defines signaling thresholds for the Ag receptor as well as other cell surface receptors that regulate B lymphocyte selection, activation, and differentiation. Defects in CD19 are a cause of hypogammaglobulinemia.

You may also be interested in the following CD19 products:
Cell Isolation
Primary Antibodies
Gene Expression Assays
For Research Use Only. Not for use in diagnostic procedures.


Form: Lyophilized
Purity: ≥ 90% by SDS-PAGE
Gene ID: 930
Species: Human
Expression: Mammalian
Gene Symbol: CD19
Gene Aliases: B4, MGC12802
Product Size: 5 x 5 µg
Protein Form: Truncated, Cell Surface Protein, Recombinant
Protein Family: CD Proteins
Endotoxin Level: < 1 EU/µg
Protein Subtype: Other Proteins
Molecular Weight: 31.6 kDa
Research Category: Immunology
Protein Tag or Fusion: His Tag
Validated Application: Assay Standard
Shipping Condition: Room Temperature

Contents & storage

Store at -20 to -70 °C


Manuals & protocols