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Proteintech
PSMA8 Polyclonal Antibody
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Product Details
14022-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PSMA8 Fusion Protein Ag5138 (1-250 aa encoded by BC042820)
Conjugate
Form
Liquid
Concentration
0.38 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASRYDRAI TVFSPDGHLF QVEYAQEAVK KGSTAVGIRG TNIVVLGVEK KSVAKLQDER TVRKICALDD HVCMAFAGLT ADARVVINRA RVECQSHKLT VEDPVTVEYI TRFIATLKQK YTQSNGRRPF GISALIVGFD DDGISRLYQT DPSGTYHAWK ANAIGRSAKT VREFLEKNYT EDAIASDSEA IKLAIKALLE VVQSGGKNIE LAIIRRNQPL KMFSAKEVEL YVTEIEKEKE EAEKKKSKKS V (1-250 aa encoded by BC042820)
Target Information
Component of the spermatoproteasome, a proteasome specifically found in testis that promotes acetylation-dependent degradation of histones, thereby participating actively to the exchange of histones during spermatogenesis. The proteasome is a protein complexe that degrades unneeded or damaged proteins by proteolysis, a chemical reaction that breaks peptide bonds. Required for 20S core proteasome assembly, essential for the degradation of meiotic proteins RAD51 and RPA1 at late prophase I and the progression of meiosis I during spermatogenesis. Localizes to the synaptonemal complex, a 'zipper'-like structure that holds homologous chromosome pairs in synapsis during meiotic prophase I. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Alpha4s; proteasome (prosome, macropain) subunit, alpha type, 8; Proteasome alpha 4 subunit; proteasome alpha 8 subunit; proteasome subunit alpha 8; proteasome subunit alpha type-7-like; Proteasome subunit alpha type-8; Proteasome subunit alpha-type 7-like; Proteasome subunit alpha-type 8
Gene Aliases: 2410072D24Rik; PSMA7L; PSMA8; RGD1311659
UniProt ID: (Human) Q8TAA3, (Mouse) Q9CWH6
Entrez Gene ID: (Human) 143471, (Mouse) 73677, (Rat) 364814
ubiquitin-dependent protein catabolic process
spermatogenesis
proteasomal protein catabolic process
cell differentiation
proteasome-mediated ubiquitin-dependent protein catabolic process
meiotic cell cycle
proteolysis involved in cellular protein catabolic process
regulation of meiosis I
proteolysis
proteasomal ubiquitin-independent protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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