Search Thermo Fisher Scientific
- Order Status
- Quick Order
-
Don't have an account ? Create Account
Element Search
Structure SearchThermo Scientific Chemicals
(+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals
Catalog number: 154980500
50g, Glass bottle, Each
Thermo Scientific Chemicals
(+)-Dehydroisoandrosterone, 99%, Thermo Scientific Chemicals
Catalog number: 154980500
50g, Glass bottle, Each
Quantity
Packaging
Chemical Identifiers
CAS
53-43-0
IUPAC Name
(3aS,3bR,7S,9aR,9bS,11aS)-7-hydroxy-9a,11a-dimethyl-1H,2H,3H,3aH,3bH,4H,6H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-one
Molecular Formula
C19H28O2
InChI Key
FMGSKLZLMKYGDP-USOAJAOKSA-N
SMILES
C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CCC2=O
Specifications
Specification SheetAppearance (Form)
Crystalline powder
Appearance (Color)
White to off-white
Infrared spectrum
Conforms
HPLC
>=98.5 %
Specific optical rotation
+11.0° to +13.0° (20°C, 589 nm) (c=2, Ethanol 96%)
Description
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• (+)-Dehydroisoandrosterone is an endogenous steroid hormone precursor that acts as an intermediate in the conversion of cholesterol to androgens and estrogens
Applications
• It is an endogenous and naturally occurring steroid hormone produced largely by the adrenal glands, but also by the testes and ovaries
• It has been described that (+)-Dehydroisoandrosterone could have a role in the immune and stress response
• (+)-Dehydroisoandrosterone can be converted to testosterone, androstenedione, estradiol, and estrone
• (+)-Dehydroisoandrosterone is derived from cholesterol through the action of two cytochrome P450 enzymes
• It can induce both direct and indirect in vivo biological effects, by modulating GABA- α receptor and N-Methyl-D-aspartic acid (NMDA) receptor complexes.
• It can also increase pancreatic β cell insulin secretion and anti-glucocorticoid activity
• It is useful to detect excess adrenal activity since it is produced nearly exclusively by the adrenal glands
RUO – Research Use Only
Figures
Documents & Downloads
Certificates
Search by lot number or partial lot number
Frequently asked questions (FAQs)
Citations & References
Search citations by name, author, journal title or abstract text