Thermo Scientific™

Proteinase K Powder (≥30 U/mg)

Catalog number:  17916

 Related applications:

Protein Labeling & Crosslinking

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Thermo Scientific Pierce Proteinase K is a protease that cleaves at the carboxyl side of aliphatic, aromatic or hydrophobic residues and is commonly used to digest and inactivate DNase and RNase in nucleic acid purification.

Proteinase K is a subtilisin-like endolytic protease that is isolated from the saprophytic fungus Tritirachium album. It has a high activity that is stable across a wide range of pH and temperature conditions and is suited to short digestion times. The activity of proteinase K is increased at elevated temperatures up to 65°C. Calcium is not essential to the function of proteinase K. Therefore, EDTA and other chelating agents do not interfere with the activity and may be used alongside proteinase K to inactivate calcium-dependent nucleases in DNA and RNA preparation.
For Research Use Only. Not for use in diagnostic procedures.


Form: Powder
Product Size: 100 mg

Contents & storage

Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, but do not store above -20°C.


Manuals & protocols