Cytokeratin (Pan) Rabbit Polyclonal Antibody, Concentrate

Catalog number: 180059

 Related applications: Anatomical Pathology

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Description

Full Product Description
Cytokeratin (CK) filaments consist of a complex family of approximately 20 different cytokeratin polypeptides that provide structural integrity to epithelial cells. Our polyclonal pan-CK antibody showed no cross-reactivity to other filament types including vimentin, desmin, glial fibrillary acidic protein and neurofilament protein. This antibody can be used to discern whether a neoplasm originated from an epithelial or non-epithelial source, and also useful for the distinction of metastatic malignant tumors of epithelial origin. Positive tissue: Adenocarcinoma⁄skin⁄squamous carcinoma.

Immunogen: Epidermal keratin subunits from bovine

Specificity: Cytokeratins (Pan)

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (Citrate, pH 6.0) OR Enzyme Digestion: Digest-All™ 3 (Pepsin) can also be used.

Expected Staining Pattern: Cytoplasmic
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Rabbit
Clonality: Polyclonal
Target Gene: Cytokeratin (Pan)
Gene ID: 3856, 3858, 3872, 3875
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 1 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

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