p53 Mouse Monoclonal Antibody (clone BP53.12), Concentrate

Catalog number: 180129

 Related applications: Anatomical Pathology

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Description

This monoclonal antibody reacts with p53, both wild type and mutant. The epitope location is between amino acids 1 and 45 in the p53 protein product. p53 is thought to act as a tumor suppressor gene in mammalian species. Mutation of p53 may represent the most common genetic event in human malignant tumors. Positive tissue: Breast carcinoma/colon cancer.

Clone/PAD: BP53.12

Immunogen: Recombinant human wild-type p53 protein

Specificity: p53

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (Citrate buffer, pH 6.0), Enzyme Digestion: Not Required

Expected Staining Pattern: Nuclear
For In Vitro Diagnostic Use.

Specifications

Reactivity: Human
Validated Application: Immunohistochemistry (FFPE)
Host Species: Mouse
SubClass (Isotype): IgG2a, kappa
Clonality: Monoclonal
Target Gene: p53
Gene ID: 7157
Label or Dye: Unconjugated
Dilution: Concentrate Antibody
Product Size: 1 mL
Shipping Condition: Wet Ice

Contents & storage

Store in refrigerator (2–8°C).

Documents

Manuals & protocols