Cytokeratin 5/6 Mouse Monoclonal Antibody (clone D5/16B4), Concentrate

Catalog number:  180267

Related applications:

Anatomical Pathology

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Description

This monoclonal antibody reacts with Cytokeratin 5/6, and reacts weakly with Cytokeratin 4. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheloid mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody to distinguish benign ductal hyperplasias from non-invasive neoplastic proliferations. Positive tissue: Skin.

Clone/PAD: D5/16B4

Immunogen: Purified Cytokeratin 5 and 6

Specificity: Cytokeratin 5&6. Weak reactivity with Cytokeratin 4.

Reactivity: Human

Applications: Immunohistochemistry (FFPE)

Pretreatment: Epitope Retrieval: Required (EDTA, pH 8), Enzyme Digestion: Not required

Expected Staining Pattern: Cytoplasmic
For In Vitro Diagnostic Use.

Specifications

Clonality: Monoclonal
Dilution: Concentrate Antibody
Gene ID: 140446, 3852, 3853, 3854
Host Species: Mouse
Label or Dye: Unconjugated
Product Size: 1 mL
Reactivity: Human
Shipping Condition: Wet Ice
SubClass (Isotype): IgG1
Target Gene: Cytokeratin 5/6
Validated Application: Immunohistochemistry (FFPE)

Contents & storage

Store in refrigerator (2–8°C).