Thermo Scientific™

CaptureSelect™ Human Albumin Affinity Matrix

Catalog number: 19129701L
Thermo Scientific™

CaptureSelect™ Human Albumin Affinity Matrix

Catalog number: 19129701L
Catalog Number
19129701L
Unit Size
1 L
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5 mL
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Price: 978.00
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10 mL
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250 mL
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50 mL
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500 mL
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5 L
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19129701L1 LContact Us ›--
1912970055 mL
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19129701010 mL
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1912970250250 mLContact Us ›--
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Product Overview
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Additional Information
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Recommendations
CaptureSelect™ Human Albumin Affinity Matrix has been specifically designed for the purification of human albumin and albumin fusion proteins.

Features of this affinity matrix include:

• Highly selective for human albumin
• Unique elution characteristics allowing for gentle elution of albumin fusion proteins
• Excellent scalability
• Non-animal-derived

The high selectivity and yields obtained using CaptureSelect™ Human Albumin Affinity Matrix enable a robust and efficient purification process with excellent purity obtained in one step. The mild elution conditions make the resin suitable for the purification of albumin fusion proteins, especially those that are pH sensitive.

Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).

Main Characteristics:

Matrix: agarose-based, aldehyde-activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect™ HSA affinity ligand
Ligand coupling method: aldehyde coupling via NH2 residues of the ligand
Binding capacity: ∼15 mg albumin/mL resin
Elution conditions (neutral pH): 20 mM Tris, pH 7.4 with 2 M MgCl2 or with 1 M NaCl + 50%(v/v) propylene glycol or with 1 M NaCl + 0.5 M L-arginine
Elution conditions (acidic pH): 0.1 M glycine, pH 3.0
Flow characteristics: 50–200 cm/h (up to 2 bar)
Formulation buffer: 20%(v/v) ethanol

Specifications

Flow Rate
200 to 400 cm/hr.
Matrix
Agarose based, aldehyde activated
Particle Size
65 micron
Form
Liquid Suspension
Column Type
Bulk Resin
Product Line
CaptureSelect™
Type
Affinity Matrix
Stationary Phase
Anti HSA

Contents & Storage

Store in refrigerator (2–8°C).