CaptureSelect Human Growth Hormone (hGH) Affinity Matrix has been specifically designed for the purification of human growth hormone from recombinant sources.
Features of this affinity matrix include: • Highly selective for recombinant hGH • Efficient purification of recombinant hGH with high yields and retained activity • Excellent scalability • Non-animal-derived
Recombinant hGH, also known as somatotropin or somatropin, is a peptide hormone that stimulates growth, cell reproduction, and regeneration in humans and other animals. The high selectivity and yields obtained using CaptureSelect Human Growth Hormone Affinity Matrix enable a robust and efficient purification process with excellent purity obtained in one step.
Free of animal components Our CaptureSelect products are affinity ligands created by a proprietary technology based on camelid-derived single-domain antibody fragments. The ligand is a 13-kDa fragment comprising the three complementarity determining regions (CDRs) that form the antigen-binding domain, efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.
Matrix: agarose-based, aldehyde-activated Average particle size: 65 ± 10 µm Ligand: CaptureSelect hGH affinity ligand Ligand coupling method: aldehyde coupling via NH2 residues of the ligand Binding capacity: ~3 mg/mL resin Elution conditions: 20 mM citric acid, pH 3.0 Flow characteristics: 50–150 cm/h (up to 1 bar) Formulation buffer: 20%(v/v) ethanol