Thermo Scientific™

CaptureSelect™ KappaXL Affinity Matrix

Catalog number: 19432101L
Thermo Scientific™

CaptureSelect™ KappaXL Affinity Matrix

Catalog number: 19432101L
Catalog Number
19432101L
Unit Size
1 L
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5 mL
Price (USD)
850.00
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50 mL
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5,100.00
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250 mL
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10 mL
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5 L
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500 mL
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19432101L1 LContact Us ›***-
1943210055 mL
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19432105050 mL
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19432105L5 LContact Us ›***-
1943210500500 mLContact Us ›***-
Product Overview
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The CaptureSelect™ KappaXL Affinity Matrix has been specifically designed for the purification of recombinant human Ig’s (including IgA, IgM, IgD, and IgE) containing a Kappa light chain and their Fab fragments.

Features of this affinity matrix include:

• Mild elution for Fab fragments and antibodies
• Human specific, no binding to bovine antibodies, for example
• Excellent scalability
• Non-animal-derived

CaptureSelect™ KappaXL Affinity Matrix purifies Ig’s, Fab, and Fab2 fragments directly from complex source materials in a single step with high purity and yield.

Free of Animal Components
Our CaptureSelect™ products are affinity ligands created by a proprietary technology based on Camelid-derived single domain antibody fragments. The ligand is a 13 kDa single domain fragment comprising the 3 CDRs that form the antigen binding domain, efficiently produced by the yeast Saccharomyces cerevisiae in a production process free of animal components.

Main Characteristics:

Matrix: agarose-based, aldehyde-activated
Average particle size: 65 ± 10 µm
Ligand: CaptureSelect™ KappaXL affinity ligand
Ligand coupling method: aldehyde coupling via NH2 residues of the ligand
Binding capacity: 29–38 g IgG/L resin depending on flow rate, column height, and contact time
Elution conditions: 20 mM citric acid, pH 3.5
Flow characteristics: 200–400 cm/h (up to 1 bar)
Formulation buffer: 20%(v/v) ethanol
Caution: For manufacturing, processing, or repacking.

Specifications

Stationary Phase
Anti LC-kappa
Column Type
Bulk Resin
Form
Liquid Suspension
Product Line
CaptureSelect™
Type
Affinity Matrix
Flow Rate
200 to 400 cm/hr.
Matrix
Agarose based, aldehyde activated
Particle Size
65 micron

Contents & Storage

Store in refrigerator (2–8°C).

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Frequently asked questions (FAQs)

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