Thermo Scientific™

MPBH (4-(4-N-maleimidophenyl)butyric acid hydrazide)

Catalog number: 22305
Thermo Scientific™

MPBH (4-(4-N-maleimidophenyl)butyric acid hydrazide)

Catalog number: 22305
Catalog Number
22305
Unit Size
50 mg
Price (USD)
Price: 413.00
Your Price:
Availability
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Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
2230550 mg
Price: 413.00
Your Price:
***
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Thermo Scientific Pierce MPBH is a long, maleimide-and-hydrazide crosslinker for conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).

Features of MPBH:

Reactive groups: maleimide and hydrazide
Reactive towards: sulfhydryl groups and carbonyl (aldehyde) groups
• Long (17.9A), sulfhydryl-to-aldehyde crosslinker with an aromatic ring in its spacer arm (noncleavable)
• Maleimide group reacts with sulfhydryl groups to form stable thioether linkages
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Use sodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use with EDC to conjugate primary amine of hydrazide group to carboxyl groups

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
BMPH
EMCH
KMUH
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Product Line
Pierce™
Labeling Method
Chemical Labeling
Crosslinker Type
Heterobifunctional
Reactive Moiety
Amine, Hydrazide, Maleimide
Spacer
Long
Form
Powder
Quantity
50 mg
Type
Crosslinker
Solubility
DMF, DMSO

Contents & Storage

Upon receipt store desiccated at 4°C. Product is shipped at ambient temperature.

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