Thermo Scientific™

SMPB (succinimidyl 4-(p-maleimidophenyl)butyrate)

Catalog number:  22416

Related applications:

Protein Labeling & Crosslinking

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Thermo Scientific Pierce SMPB is an amine-to-sulfhydryl crosslinker that contains NHS-ester and maleimide reactive groups at opposite ends of a medium-length aromatic spacer arm (11.6 angstroms).

Features of SMPB:

Reactive groups: NHS ester and maleimide
Reactive towards: amino and sulfhydryl groups
• Extended chain analog of MBS
• Non-cleavable
• Water-insoluble (dissolve first in DMF or DMSO)
• Conjugates formed with SMPB are more stable in serum than SPDP conjugates

Product References:
Crosslinker Application Guide -- search for recent literature references for this product

Related Products
Sulfo-SMPB (sulfosuccinimidyl 4-(N-maleimidophenyl)butyrate)
For Research Use Only. Not for use in diagnostic procedures.


Product Line: Pierce™
Crosslinker Type: Heterobifunctional
Form: Solid
Labeling Method: Chemical Labeling
Reactive Moiety: Maleimide, NHS Ester
Solubility: DMSO (Dimethylsulfoxide), DMF (Dimethylformamide)
Spacer: Mid-Length
Product Type: Crosslinker
Quantity: 50 mg

Contents & storage

Upon receipt store desiccated at -20°C. Product is shipped at ambient temperature.