Thermo Scientific Pierce SPB is an NHS-ester and psoralen crosslinker that effectively conjugates primary amines to DNA via light-activated intercalation next to pyrimidine bases.
Features of SPB:
• Reactive groups: NHS ester and psoralen • Reactive toward: amino groups and thymine • DNA intercalating agent and nucleic acid probe1,2 • Reagent for photo-immobilization to microplates3 • Melting point: 177-178°C
Product References: Crosslinker Application Guide -- search for recent literature references for this product
For Research Use Only. Not for use in diagnostic procedures.