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Thermo Scientific Chemicals
Tetracycline hydrochloride, can be used as secondary standard
Tetracycline hydrochloride, CAS # 64-75-5, is a wide-spectrum antibiotic that targets both gram-negative and gram-positive bacteria.
化学物質識別子
CAS64-75-5
IUPAC Namehydrogen (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-1,2,3,4,4a,5,5a,6,12,12a-decahydrotetracene-1,3,12-trione chloride
Molecular FormulaC22H25ClN2O8
InChI KeyDYQBMRZOOXYHIM-NCKOGSTASA-N
SMILES[H+].[Cl-].CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)C4=C(O)C=CC=C4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(\N)O)C1=O
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仕様
スペックシート
スペックシートInfrared spectrumConforms
Purity>=80 % (as is, calculated)
Appearance (Color)Yellow
Appearance (Form)Powder
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Tetracycline hydrochloride is the hydrochloride salt of
the antibiotic tetracycline
• Tetracycline blocks amino acyl-tRNA binding during
bacterial protein synthesis
• Tetracycline is a broad-spectrum naphthacene antibiotic that
inhibits growth of both gram positive and gram negative bacteria
Applications
• Tetracycline may be used as a selection agent in cell
culture
• It may also be used to activate inducible gene
expression in engineered cells
RUO – Research Use Only
Literature references
Chopra, I.; Roberts, M. Tetracycline antibiotics: mode of
action, applications, molecular biology, and epidemiology of bacterial
resistance. Microbiol Mol Biol Rev. 2001, 65(2), 232-60.
Kenny, P.A.; Enver, T., Ashworth, A. Retroviral vectors for
establishing tetracycline-regulated gene expression in an otherwise
recalcitrant cell line. BMC Mol Biol. 2002, 3:13.