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Proteintech
FEV Polyclonal Antibody
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Product Details
25058-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FEV Fusion Protein Ag20647 (1-238 aa encoded by BC023511)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MRQSGASQP LLINMYLPDP VGDGLFKDGK NPSWGPLSPA VQKGSGQIQL WQFLLELLAD RANAGCIAWE GGHGEFKLTD PDEVARRWGE RKSKPNMNYD KLSRALRYYY DKNIMSKVHG KRYAYRFDFQ GLAQACQPPP AHAHAAAAAA AAAAAAQDGA LYKLPAGLAP LPFPGLSKLN LMAASAGVAP AGFSYWPGPG PAATAAAATA ALYPSPSLQP PPGPFGAVAA ASHLGGHYH (1-238 aa encoded by BC023511 )
Target Information
This gene belongs to the ETS transcription factor family. ETS family members have a highly conserved 85-amino acid ETS domain that binds purine-rich DNA sequences. The alanine-rich C-terminus of this gene indicates that it may act as a transcription repressor. This gene is exclusively expressed in neurons of the central serotonin (5-HT) system, a system implicated in the pathogeny of such psychiatric diseases as depression, anxiety, and eating disorders. In some types of Ewing tumors, this gene is fused to the Ewing sarcoma (EWS) gene following chromosome translocations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ETS-domain transcription factor Pet-1; FEV (ETS oncogene family); FEV (fifth Ewing variant); FEV, ETS transcription factor; Fifth Ewing variant protein; PC12 ETS domain-containing transcription factor 1; PC12 ETS factor 1; pheochromocytoma 12 ETS (E26 transformation-specific); Protein FEV
Gene Aliases: FEV; HSRNAFEV; mPet-1; PET-1; PET1
UniProt ID: (Human) Q99581, (Mouse) Q8QZW2
Entrez Gene ID: (Human) 54738, (Mouse) 260298
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
winged helix/forkhead transcription factor
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
nervous system development
positive regulation of gene expression
cell differentiation
neuron maturation
maternal behavior
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
neuron fate specification
transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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