Thermo Scientific™

Pierce™ Sulfo-NHS-Acetate

Catalog number:  26777

 Related applications:

Protein Labeling & Crosslinking

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Thermo Scientific Pierce Sulfo-NHS-Acetate is a small compound used for blocking primary amines (e.g., lysine side chains). This compound forms stable, covalent amide bonds with amine groups to prevent specific interactions or conjugations.

Sulfo-NHS-Acetate is typically used to prevent polymerization when performing protein crosslinking reactions and when conjugating peptides to carrier proteins for immunogen production. Blocking amines on the peptide allows directed conjugation of carboxylic acids on the peptide to primary amines on the protein using EDC.

Features of Sulfo-NHS-Acetate:

• Irreversibly block primary amines
• Perform reactions in standard non-amine-containing buffers at pH 7 or greater
• Prevent polymerization when performing protein crosslinking reactions
For Research Use Only. Not for use in diagnostic procedures.


Chemical Reactivity: Amine
Label or Dye: Unreactive Group
Product Line: Pierce™
Product Size: 100 mg
Solubility: DMF (Dimethylformamide), DMSO (Dimethylsulfoxide), Water
Spacer: Short

Contents & storage

Upon receipt store desiccated at -20° C. Product is shipped at ambient temperature.


Manuals & protocols