Thermo Scientific™

8-oxo-dG Phosphoramidite, standard grade, serum vial bottle

Catalog number:  27-1424-04

 Related applications:

Nucleic Acid Labeling & Oligo Synthesis

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Description

8-oxo-dG CEP is a phosphoramidite containing an oxidized deoxyguanosine (dG), and it facilitates the investigation of the structure and activity when incorporated into an oligonucleotide. In nature, 8-oxo-dG DNA lesions are formed with reactive oxygen species (ROS), and is removed by by the base excision repair (BER) mechanism. This modification is significant in mutagenesis, carcinogenesis, and has been proven useful as a biomarker. This product is supplied in a 5 mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers of oligonucleotide synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)‑N2-isobutyryl-8-oxo-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H54N7O9P
• Base—8-oxo-dG
• Base Protection—iBu
• Formula weight—855.9 g/mol
• CAS number—143060-53-1
• HPLC Purity—≥98.0%
• 31P NMR Purity—≥98.0%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Nucleic Acid Type: DNA
Nucleoside Type: Deoxyguanosine (dG)
Chemical Name: 8-oxo-dG CEP
For Use With (Equipment): AKTA Synthesizers, Applied Biosystems Synthesizers
Form: Powder
Product Size: 0.25 g
Purity or Quality Grade: Standard
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature

Contents & storage

Store in freezer (at or below -20°C).

Documents

Manuals & protocols