Thermo Scientific™

2'-Fluoro-U Phosphoramidite, TheraPure™ grade, 28-400 finish bottle

Catalog number: 27-1602-12
Thermo Scientific™

2'-Fluoro-U Phosphoramidite, TheraPure™ grade, 28-400 finish bottle

Catalog number: 27-1602-12
Catalog Number
27-1602-12
Unit Size
0.5 g
Price (USD)
81.00
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-1602-120.5 g
81.00
Your Price:
***
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2'-Fluoro-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 30-mL amber bottle with a 28-400 finish neck style, which is compatible with most MerMade synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-2'-fluorouridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C39H46FN4O8P
• Base—A
• Formula weight—748.8 g/mol
• CAS number—146954-75-8
• HPLC purity—>98%
31P NMR purity—≥98%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Product Line
TheraPure™
Format
Powder
For Use With (Equipment)
MerMade Synthesizers
Product Type
2in-Fluoro-U CEP
Nucleoside Type
Uridine (U)
Reagent Features
2in-Fluoro modified
Shipping Condition
Room Temperature
Purity
98%
Reagent Type
Phosphoramidite
Grade
TheraPure™
Nucleic Acid Type
RNA

Contents & Storage

Store in freezer (at or below -20°C).

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