Thermo Scientific™

2'-Fluoro-iBu-G Phosphoramidite, standard grade, 20-400 finish bottle

Catalog number: 27-1607-09
Thermo Scientific™

2'-Fluoro-iBu-G Phosphoramidite, standard grade, 20-400 finish bottle

Catalog number: 27-1607-09
Catalog Number
27-1607-09
also known as 27-1607-12
Unit Size
0.25 g
Price (USD)
45.55
Your Price:
Availability
***
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-1607-09
also known as 27-1607-12
0.25 g
45.55
Your Price:
***
Product Overview
Figures
Videos
Documents
FAQ
Citations & References
Additional Information
Recommendations
Recommendations
2'-Fluoro-iBu-G CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with 2'-Fluoro protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, the highly electronegative fluorine (2'-Fluoro) modification adopts a more thermodynamically stable A-form helix on hybridization to its target. Showing improved affinity and some nuclease resistance (compared to 2'-OH), the 2'-F modification has been proven useful in antisense, siRNA, and aptamer applications. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-fluoroguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H53FN7O8P
• Base—G
• Base Protection—iBu
• Formula weight—857.4 g/mol
• CAS number—144089-97-4
• HPLC purity—>98%
31P NMR purity—≥98%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Format
Powder
For Use With (Equipment)
Expedite Synthesizers
Product Type
2in-Fluoro-iBu-G CEP
Nucleoside Type
Guanosine (G)
Reagent Features
2in-Fluoro modified
Shipping Condition
Room Temperature
Purity
98%
Reagent Type
Phosphoramidite
Grade
Standard
Nucleic Acid Type
RNA

Contents & Storage

Store in freezer (at or below -20°C).

Figures

Frequently asked questions (FAQs)

Citations & References