Thermo Scientific™

PAC-dA Phosphoramidite, standard grade, serum vial bottle

Catalog number:  27-1723-04

 Related applications:

Nucleic Acid Labeling & Oligo Synthesis

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Description

PAC-dA CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyadenosine (dA) with Phenoxyacetyl (PAC) base protection, for use in oligonucleotide synthesis. The UltraMILD monomers - phenoxyacetyl (PAC)-dA, acetyl (Ac)-dC, and iso-propyl-phenoxyacetyl (iPr-PAC)-dG - were developed to alleviate the problem of modifiers and labels not withstanding prolonged exposure to strongly alkaline deprotection conditions. Cleavage and deprotection can be achieved in 4 hours at room temperature with 0.05M potassium carbonate in methanol. The "Standard Grade" marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 20 mL Amber bottle with a Serum Vial neck style, which is compatible with most ABI Systems|AKTA Systems of oligonucleotide synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N6-phenoxyacetyl-2'-deoxyadenosine-3'-O- [(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C48H54N7O8P
• Base—dA
• Base Protection—PAC
• Formula weight—887.96 g/mol
• CAS number—110543-74-3
• HPLC Purity—≥98.0%
• 31P NMR Purity—≥98.0%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Nucleic Acid Type: DNA
Nucleoside Type: Deoxyadenosine (dA)
Reagent Features: Fast deprotection
Chemical Name: PAC-dA CEP
For Use With (Equipment): AKTA Synthesizers, Applied Biosystems Synthesizers
Form: Powder
Product Size: 1 g
Purity or Quality Grade: Standard
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature

Contents & storage

Store in freezer (at or below -20°C).

Documents

Manuals & protocols