dU CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxyuridine (dU) for use in oligonucleotide synthesis. The incorporation of a deoxyuridine base into a DNA sequence can be utilized to induce mutagenic effects. Enzymatically the uracil is removed, creating an abasic site at the dU position, and thus generating site-specific breaks in the oligo. This product is supplied in a 20 mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers of oligonucleotide synthesizers.
Features: • Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite • Molecular formula—C39H47N4O8P • Base—dU • Formula weight—730.8 g/mol • CAS number—144385-59-1 • HPLC Purity—≥98.0%; conforms to reference • 31P NMR Purity—≥98.0%; conforms to reference
For Use With (Equipment)
AKTA Synthesizers, Applied Biosystems Synthesizers