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Thermo Scientific™

2'-OMe-U Phosphoramidite, standard grade, 20-400 finish bottle

Catalog number: 27-1825-10
Thermo Scientific™

2'-OMe-U Phosphoramidite, standard grade, 20-400 finish bottle

Catalog number: 27-1825-10
Catalog Number
27-1825-10
Unit Size
1 g
Price (USD)
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
27-1825-101 g
-
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2'-OMe-U CEP is a phosphoramidite containing 5' DMT and the nucleoside uridine (U) with 2'-O-methyl protection, for use in oligonucleotide synthesis. Located in the ideal oligo position, 2'-O-methyl (OMe) oligo modifications display nuclease resistance, fewer off-target effects, and slightly increased hybridization affinities. These phosphoramidites are commonly used for oligos designed for antisense, siRNA, aptamer, or gRNA-based research. The 'standard grade' marking denotes a baseline level of purity verified with analytical methods, and proven to be suitable for most oligo synthesis requirements. This product is supplied in a 30-mL amber bottle with a 20-400 finish neck style, which is compatible with most Expedite synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyl-uridine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C40H56N7O9P
• Base—U
• Formula weight—760.8 g/mol
• CAS number—110764-79-9
• HPLC purity—≥98.0%; Sum of non-primary peaks at 140-152ppm: ≤0.5%
31P NMR purity—≥98.0%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

For Use With (Equipment)
Expedite Synthesizers
Product Type
2in-OMe-U CEP
Nucleoside Type
Uridine (U)
Reagent Features
2in-OMe modified
Shipping Condition
Room Temperature
Purity
98%
Quantity
1 g
Reagent Type
Phosphoramidite
Grade
Standard
Nucleic Acid Type
RNA
Form
Powder

Contents & Storage

Store in freezer (at or below -20°C).

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