Thermo Scientific™

Bz-dC Phosphoramidite, TheraPure™ grade, 28-400 finish bottle

Catalog number:  27-2032-14

 Related applications:

Nucleic Acid Labeling & Oligo Synthesis

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Description

Bz-dC CEP is a phosphoramidite containing 5' DMT and the nucleoside deoxycytidine (dC) with Benzoyl (Bz) base protection, for use in oligonucleotide synthesis. DNA phosphoramidites are the building blocks for synthesis of DNA or DNA containing oligonucleotides. Each base has unique protecting groups designed specifically to protect the DNA during the chemical synthesis process, and produce the highest amount of full length product. Alternative protecting groups on dC (acetyl) and dG (DMF) allow for a faster deprotection of the oligonucleotide. The TheraPure trademark denotes a highest level of phosphoramidite purity, developed with the highest stringency of of high definiteion analytics and tightly controlled impurity profiles. Ideal for any therapeutic application. This product is supplied in a 250 mL Amber bottle with a 28-400 Finish neck style, which is compatible with most MerMade Systems of oligonucleotide synthesizers.

Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)-N4-benzoyl-2'-deoxycytidine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C46H52N5O8P
• Base—dC
• Base Protection—Bz
• Formula weight—833.93 g/mol
• CAS number—102212-98-6
• HPLC Purity—≥99%; M-11 Impurity ≤0.01%; Single critical impurity ≤0.3%; Presence of dA, dG, or T impurity ≤0.03%
• 31P NMR Purity—≥99%; Sum of non-primary peaks at 140-152 ppm: ≤0.3%; No peak(s) above 170 ppm; HMT impurity (~146ppm): ≤0.10%

For Research Use Only. Not for use in diagnostic procedures.

Specifications

Nucleic Acid Type: DNA
Nucleoside Type: Deoxycytidine (dC)
Chemical Name: Bz-dC CEP
For Use With (Equipment): MerMade Synthesizers
Form: Powder
Product Line: TheraPure™
Product Size: 10 g
Purity or Quality Grade: TheraPure™
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature

Contents & storage

Store in freezer (at or below -20°C).

Documents

Manuals & protocols