Power-Bind™ Streptavidin Coated Particles
Power-Bind™ Streptavidin Coated Particles
Thermo Scientific™

Power-Bind™ Streptavidin Coated Particles

Bind a variety of biotinylated ligands, including DNA/RNA, oligos, antibodies and proteins with Thermo Scientific™ Power-Bind Streptavidin Coated Particles.
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Catalog NumberQuantityDiameter (Metric)
290018010111501 mL0.85 μm
290007010101505 mL0.3 μm
29000701010350100 mL0.3 μm
290007010111501 mL0.3 μm
290018010101505 mL0.85 μm
29001801010350100 mL0.85 μm
Catalog number 29001801011150
Price (USD)/ Each
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Quantity:
1 mL
Diameter (Metric):
0.85 μm
Bind a variety of biotinylated ligands, including DNA/RNA, oligos, antibodies and proteins with Thermo Scientific™ Power-Bind Streptavidin Coated Particles. Particles have very high and stable biotin binding capacities and address the concerns of diagnostic test kit manufacturers and nucleic acid researchers. The microparticles reduce serum matrix effects and improve assay accuracy, resulting in low, non-specific binding of serum proteins and other interfering substances.
The use of microparticles as a solid phase support in various immunoassays and affinity purifications has been known for some time; however, achieving high activity and stable binding of solid phase ligands has been a major difficulty. Biotinylated compounds become stably bound to Power-Bind Streptavidin Coated particles after simple incubation in buffer due to the high affinity of the biotin-streptavidin interaction. The particles also function as a spacer, which improves the specific activity of the bound ligand. Monodisperse nonmagnetic particle suspensions with streptavidin covalently bound to the surface in a highly active form

Features:

  • Made from 0.3μm or 0.8μm Thermo Scientific™ OptiLink™ Carboxylate-Modified particles
  • High biotin-binding capacity
  • Extremely stable, long shelf life
  • Simplifies the process of binding ligands to particles
  • Combines the advantages of high surface area and easy, high affinity, high specific activity binding
  • Excellent for chemiluminescent assays, biotinylated ligand capture, and for molecular biology, immunoassay, or sample prep applications

Benefits:

  • Dissociation constant (Kd 10-15 molar), easy one-step binding protocols for biotinylated ligands
  • High activity of surface bound ligands to easily solve difficult coupling problems
  • Simple aqueous biotinylation reactions
  • Low nonspecific interactions (blocked microparticle surface)
  • Highly mobile particles for membrane-based applications
  • Can be used in EIA formats with biotin/enzyme detection systems
  • Beneficial spacer effect of SA molecule
  • A choice of 0.3μm or 0.8μm diameters for different application requirements

Recommended for:

  • Universal nonmagnetic bead for coupling unique ligands.
  • Clinical diagnostics and molecular biology applications.
Specifications
Certifications/ComplianceIncludes Certificate of Analysis
DescriptionPower-Bind Streptavidin Coated Particles
ColorWhite or Colorless
For Use With (Application)Biotinylated Ligand Binding, Diagnostic Assays
MaterialPolystyrene
Product TypeStreptavidin-Coated Particles
IncludesPackage Insert and Certificate of Analysis
Preservative0.05% Na Az
Quantity1 mL
Sample Evaluation PacksPower-Bind evaluation samples are packaged in 1mL bottles at 1% solids (10 mg/mL). Select individual lots to evaluate.
Shelf Life24 Months
Specialty PackagingPower-Bind Streptavidin Coated particles are available in different concentrations and package sizes upon request.
StabilityGuanidinium thiocyanate; DMF and DMSO to 100% Sonication; environments PCR temperature cycling
Diameter (Metric)0.85 μm
Unit SizeEach
Contents & Storage
2°C to 8°C