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Fumonisin B2, 96+%, Thermo Scientific Chemicals
製品番号（カタログ番号）： 328260010
1 mg, Each
化学物質識別子
CAS
116355-84-1
仕様
スペックシートHPLC
>=96.0 %
Appearance (Color)
White to light yellow to brown
Appearance (Form)
Solid
概要
This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Fumonisin B2 is a fumonisin mycotoxin produced by the fungus Fusarium
• Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than B1 and can inhibit sphinganine-N-acetyltransferase (ceramide synthase)
Applications
• In vitro and in vivo studies have shown Fumonisin B2 can induce apoptosis
• It can inhibit de novo sphingolipid biosynthesis
• It is also considered an Aspergillus metabolite
• It shows cytotoxicity against a panel of seven rat hepatoma cell lines, and MDCK cell line
• It induces hepatocyte nodule formation, a marker of cancer initiation, in rats
RUO – Research Use Only
図
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