Thermo Scientific Chemicals

Paclitaxel, 99+%

Catalog number: 328420050
5 mg, Each
Thermo Scientific Chemicals

Paclitaxel, 99+%

Catalog number: 328420050
5 mg, Each
Quantity
Catalog number: 328420050
Price (USD)
Quantity
-

Chemical Identifiers

CAS
33069-62-4
IUPAC Name
(1S,2S,4S,7R,9S,10S,12R,15S)-4,12-bis(acetyloxy)-1,9-dihydroxy-15-{[(2R,3S)-2-hydroxy-3-phenyl-3-(phenylformamido)propanoyl]oxy}-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.0³,¹⁰.0⁴,⁷]heptadec-13-en-2-yl benzoate
Molecular Formula
C47H51NO14
InChI Key
RCINICONZNJXQF-VAZQATRQSA-N
SMILES
CC(=O)O[C@@H]1C2=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)C3=CC=CC=C3)C3[C@@]4(CO[C@@H]4C[C@H](O)[C@@]3(C)C1=O)OC(C)=O)C2(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)C1=CC=CC=C1)C1=CC=CC=C1
Appearance (Color)
White
Appearance (Form)
Powder
Infrared spectrum
Conforms
Melting point
203°C to 223°C
HPLC
>=99.0 %

Description

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
Paclitaxel is a naturally ocurring compound originally isolated from the tree T. brevifolia
Paclitaxel binds tubulin and stabilizes microtubule formation, preventing disassembly
Paclitaxel is used as a drug to arrest cells at the mitotic checkpoint and block cell cycle progression, thus inducing death of cancer cells
Applications
Paclitaxel can be used in preclinical laboratory research on diseases such as cancer, heart disease, inflammatory disorders, and hepatic fibrosis
Paclitaxel can be used as a tool in cell biology to study mitotic checkpoint arrest conditions and downstream signaling cascades
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

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