Informational:Informational:For Research Use Only. Not for use in diagnostic procedures.

Captopril, 98%, ACROS Organics™

Catalog number: 343700250

Captopril, 98%, ACROS Organics™

Catalog number: 343700250
Catalog Number
343700250
Unit Size
Each
Price (USD)
Catalog Number
Unit Size
Each
Price (USD)
Catalog Number
Unit Size
Each
Price (USD)
Catalog NumberUnit SizePrice (USD)
343700250EachContact Us ›
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POROS™ MabCapture™ G Select Resin is a high-throughput, lower-priced Protein G chromatography resin manufactured using our own Protein G ligand to enable high-throughput purification performance. It is used in a variety of antibody affinity purification methods and is ideal for polyclonal IgG purification from mouse, human, cow, goat, and sheep serum, including human IgG3 and mouse IgG1 isotypes. POROS MabCapture G Select Resin demonstrates high dynamic binding performance at low linear flow rates and maintains superior binding capacity at high linear flow rates where other chromatography media products cannot operate.

With POROS MabCapture G affinity chromatography resin you can:
• Maintain high dynamic binding capacity at liner flow rates over 700 cm/hr
• Design processes with greater flexibility (shorter bed heights, faster flow rates, or both) due to the improvements made to the antibody binding efficiency
• Obtain the highest dynamic binding capacity for antibodies vs. conventional agarose- or silica-based Protein G resins
• Purify polyclonal IgG from mouse, human, cow, goat, and sheep serum, including human IgG3 and mouse IgG1 isotypes
• Sanitize and depyrogenate with standard agents used for other chromatography products
• Recognize major increases to process productivity and reduce the downstream bottleneck

Protein G is a bacterial cell wall protein isolated from group G Streptococci. Recombinant Protein G has been modified to eliminate its binding to albumin. The Protein G molecule contains two binding domains. Although the tertiary structures of Protein A and Protein G are very similar, their amino acid compositions differ significantly, resulting in different binding characteristics. Protein G has greater affinity than Protein A for most mammalian IgGs, especially for certain subclasses, including human IgG3, mouse IgG1, and rat IgG2a. Unlike Protein A, Protein G does not bind to human IgM, IgD, and IgA.

The development of humanized monoclonal antibodies has continued to fuel the growth of the biotherapeutic market. Addressing the therapeutic demand for monoclonal antibodies has led to major improvements to the cell-based expression systems that are used to manufacture these proteins. Consequently, these improvements have moved the processing bottleneck from upstream cell expression to downstream purification. The introduction of POROS MabCapture G Select chromatography resin was aimed at cracking open the downstream bottleneck and providing the capacity, efficiency, and flexibility needed to make improvements to the downstream purification platform, resulting in major increases to process productivity and antibody manufacturing.

WARNING: Reproductive Harm - www.P65Warnings.ca.gov

Specifications

Chemical Name or Material
Captopril
Name Note
98%
CAS
62571-86-2
Health Hazard 1
GHS Signal Word: Danger
Health Hazard 2
GHS H Statement
May cause an allergic skin reaction.
Causes serious eye damage.
May damage the unborn child.
Health Hazard 3
GHS P Statement
IF ON SKIN: Wash with plenty of soap and water.
IF IN EYES: Rinse cautiously with water for several minutes.
Remove contact lenses,if present and easy to do.
Continue rinsing.
Immediately call a POISON CENTER or doc
RTECS Number
UY0550000
EINECS Number
263-607-1
Color
White
Melting Point
103.0°C to 108.0°C
Assay Percent Range
97.5% min. (HPLC)
Infrared Spectrum
Authentic
Molecular Formula
C9H15NO3S
MDL Number
MFCD00168073
Packaging
Glass bottle
Merck Index
15, 1776
Synonym
captopril, capoten, l-captopril, captopryl, lopirin, cesplon, captolane, tensoprel, acepress, captoril
Quantity
25g
Solubility Information
Solubility in water: soluble. Other solubilities: freely soluble in alcohol,chloroform,methylenech,loride
InChI Key
FAKRSMQSSFJEIM-RQJHMYQMSA-N
SMILES
CC(CS)C(=O)N1CCCC1C(=O)O
IUPAC Name
(2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
Specific Rotation
− 129.50
Molecular Weight (g/mol)
217.28
PubChem CID
44093
ChEBI
CHEBI:3380
Formula Weight
217.28
Physical Form
Crystalline Powder
Percent Purity
98%

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