Hemin, 98%, porcine

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Hemin, 98%, porcine

Name: Hemin, 98%, porcine
SKU: 345960050

Hemin, 98%, porcine, CAS # 16009-13-5, is an oxidized version of heme. It is an iron-containing prosthetic group in several proteins, and can be an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion. | CAS: 16009-13-5 | C34H32FeN4O4 | 616.50 g/mol

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Catalog number 345960050

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Glass bottle

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Chemical Identifiers

CAS16009-13-5

IUPAC Name3-[(1Z,6Z,12Z,17Z)-5-(2-carboxyethyl)-22-chloro-15,20-diethenyl-4,10,14,19-tetramethyl-21,23,24,25-tetraaza-22-ferrahexacyclo[9.9.3.1³,⁶.1¹³,¹⁶.0⁸,²³.0¹⁸,²¹]pentacosa-1,3(25),4,6,8,10,12,14,16(24),17,19-undecaen-9-yl]propanoic acid

Molecular FormulaC34H32ClFeN4O4

InChI KeyBTIJJDXEELBZFS-HXFTUNQESA-K

SMILESCC1=C(CCC(O)=O)\C2=C\C3=C(CCC(O)=O)C(C)=C4\C=C5/N=C(/C=C6\N([Fe](Cl)N34)\C(=C/C1=N2)C(C=C)=C6C)C(C=C)=C5C

Specifications

Specification Sheet

Infrared spectrumConforms

Appearance (Form)Powder or crystals

HPLC>=97.5 %

Appearance (Color)Violet to blue-black

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Hemin derived from porcine is an iron-containing prosthetic group present in some proteins and can be an alternative source of iron within the host that contains a porphyrin ring containing a Fe2+ ion

Applications

• Hemin is a protoporphyrin IX containing a ferric iron (Fe3+) ion with a coordinating chloride ligand

• It is used in cellular protection and controls biological mechanisms

• It can stimulate globulin synthesis

• It can be applied to study bacterial strains and growth conditions in the short-term colony assays and cell transfections

• It is used during the preparation of agar medium for bacteria culture

• This compound has been used in L929 and J774 murine macrophage cells in order to study conjugation, characterization and toxicity of lipophosphoglycan-polyacrylic acid conjugate for vaccination against leishmaniasis

RUO – Research Use Only

General References:

Topuzogullari, M.; Cakir, Koc R., Dincer, Isoglu, S.; Bagirova, M.: Akdeste, Z.; Elcicek, S.; Oztel, O.N.; Yesilkir, Baydar, S.; Canim, Ates, S., Allahverdiyev, A.M. Conjugation, characterization and toxicity of lipophosphoglycan-polyacrylic acid conjugate for vaccination against leishmaniasis. J Biomed Sci. 2013 Jun 3;20(1):35.
Lu, C. H.; Guo, W.; Qi, X. J.; Neubauer, A.; Paltiel, Y.; Willner, I. Hemin-G-quadruplex-crosslinked poly-N-isopropylacrylamide hydrogel: a catalytic matrix for the deposition of conductive polyaniline. Chem. Sci. 2015, 6 (11), 6659-6664.
Preda, L.; Negrila, C.; Lazarescu, M. F.; Anastasescu, M.; Dobrescu, G.; Santos, E.; Lazarescu, V. Hemin interaction with bare and 4,4'-thio-bis-benzene-thiolate covered n-GaAs (110) electrodes. Phys. Chem. Chem. Phys. 2011, 13 (38), 17104-17114.