Thermo Scientific™

Pierce™ Iodoacetic Acid

Catalog number: 35603
Thermo Scientific™

Pierce™ Iodoacetic Acid

Catalog number: 35603
Catalog Number
35603
Unit Size
500 mg
Price (USD)
Price: 107.00
Your Price:
Availability
-
Quantity
Catalog NumberUnit SizePrice (USD)AvailabilityQuantity
35603500 mg
Price: 107.00
Your Price:
-
Product Overview
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Thermo Scientific Pierce Iodoacetic Acid (IAA) can react with several protein functional groups but is typically used for specific S-carboxymethylation of sulfhydryls (reduced cysteines).

Features of Pierce Iodocetic Acid (IAA):

• React at slightly alkaline pH for specific S-carboxymethylation of free sulfhydryls
• React at low pH for specific carboxymethylation of methionines
• React at high pH to favor carboxymethylation of histidines and lysines
• Methylate reduced cysteine peptide fragments in protease digests for mass spectrometry

Iodoacetic acid reacts with sulfhydryls on cysteines, imidazolyl side chain nitrogens of histidines, the thioether of methionine and the primary amine group of lysines.The rate of reaction and specificity is dependent on the ionization level, which can be manipulated by the pH of the reaction condition.

Related Products
Pierce™ Iodoacetamide, Single-Use
For Research Use Only. Not for use in diagnostic procedures.

Specifications

Chemical Reactivity
Thiol
Description
Iodoacetic Acid
Label or Dye
Unreactive Group
Label Type
Blocking Groups
Product Line
Pierce™
Spacer
Short
Form
Powder
Quantity
500 mg
Solubility
Water
Product Type
Iodoacetic Acid

Contents & Storage

Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, between the following temperatures: 2 to 8°C.