For highly predictable and consistent extraction and isolation of genomic DNA from human whole blood, following a simple separation protocol. Isolates linear DNA yields relative to the number of white blood cells (WBC) present in the sample. The 1 µm Dynabeads™ have an optimized silica-like surface chemistry and a high specific surface area, providing efficient kinetics and a high capacity.

Their uniform size and surface area ensure highly reproducible results and an improved performance compared to magnetic particles from alternative suppliers. Other particles often have a random size range distribution, surface area and binding capacity. This could compromise the reproducibility of your results. Dynabeads™ hold reputable Dynal high standards with respect to within- and between-lot reproducibility and automation ability.

Advantages:

• Highly predictable binding per mg of beads
• Linear range of DNA yield relative to WBC-count
• High integrity and purity of isolated DNA
• Isolates 10 µg DNA from a 350 µl blood sample using 2 mg (50 µl) Dynabeads™
• Quicker than spin-columns
• More cost-effective, yet performs to the same level as spin-columns
• Automation-friendly (slow sedimentation rate + high magnetic mobility)

Applications
• Isolation of genomic DNA
• From cells and fresh/frozen blood samples
• From blood with a wide range of anticoagulants
• Well suited for automated assays
• Separate kit available for the isolation of viral DNA/RNA (Cat. no. 370-11D)

Additional Info:
Validation and customization (bead, buffer, protocol or format) can be made available on a custom OEM basis. For further information, please contact us at: ivd@invitrogen.com